Year: 2015 | Month: June and December | Volume 4 | Issue 1&2
Tumor Cells and Microvessels in Pediatric Brain Tumors
Abstract:
Brain tumors represent the most common solid tumor in children and are the leading cause of cancer-related mortality in childhood. Despite modern advances in surgery, radiation, and chemotherapy, a significant proportion of the pediatric brain tumor patients still die of their disease or suffer from poor quality of life. Therefore, more effective and alternative therapies are still in urgent need. Tumor cell lines derived from central nervous system tumors are critical tools for carrying out preclinical therapeutic testing and studying the biology of the disease. However, to date only few continuous pediatric brain tumor cell lines have been established.
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