Year: 2025 | Month: December | Volume 15 | Issue 6
Bioengineered Microbes: The Dawn of Living Therapeutics
Sanmeet Kour
Deepti Narang
Ram Saran Sethi
Amreena Hassan and Shruthi Reddy
DOI:10.30954/2277-940X.06.2025.1
Abstract:
Microbes are no longer viewed solely as vicious pathogens; they are recognized as pivotal players in human and animal health.
The innate ability of microbes to interact with host systems provides a unique platform for the delivery of therapeutics via
genetic engineering. “Designer” or bioengineered microbes represent a breakthrough for treating challenging chronic diseases
such as cancer and addressing the alarming rise in antibiotic-resistant pathogens. These living therapeutics can be programmed
to produce hormones, enzymes, antigens, and vitamins at the site of disease. As safety concerns regarding recombinant DNA
persist, the development of sophisticated biocontainment devices offers a path forward. This review explores the architecture,
applications, and challenges of bioengineered microbes as a judicious alternative to traditional antibiotics.
© This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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