Year: 2013 | Month: December | volume 2 | issue 2
Multimodal Analgesia Prolongs Duration of Postoperative Analgesia and Decreases Postoperative Pain Intensity in Short Surgical Procedures: a Randomized Controlled Trial.
Abstract: <div><b>Background</b>: We examined the effect of preoperative combination of different analgesics and the role of each individual analgesic compared to control regarding postoperative pain,</div><div><b>Methods</b>: patients were randomly allocated into either control; multiple treatment, perfalgan, opioid and voltaren group. The time for first request for analgesia and visual analogue score were compared by analysis of variance and tuckey Kramer test.</div><div><b>Results</b>:There was a main effect of treatment p>0.0001 in favor of multi-analgesia and opioid groups. Multi-analgesia group was better than opioid group p=0.016. There was a little improvement with paracetamol (perfalgan) but no effect of voltaren on duration of analgesia nevertheless;both have reduced VAS relative to control.</div><div><b>Conclusion</b>: Combination ofnon-opioid analgesicsDiclofenac Na (voltaren),</div><div>Paracetamol (perfalgan) with low dose morphine and dexamethasone have greatly prolonged duration of analgesia and reduced pain intensity without displaying notable side effects.</div>
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