Health is considered as one of the major priorities of each and every individual, organization, institutions and Government. The advancement of health and medical services have reached from infancy to the development phase. Today, several tools and technologies are being practiced for the modernizing of medical and health services, where information technology (IT) is one of them, to support healthcare sectors directly and indirectly in achieving quality health care. The affiliation and interaction between medical science and information science creates so many new domains and nomenclature, such as; Health Informatics, Medical Informatics, Medical Information Science, Health Information System and so on. These domains offer many possibilities and opportunities of Health and Medical based Information Science education programs to create a workforce to assist healthcare providers in managing hospital and population based health information system. This paper deals with the benefit and advantages of health and medical information science and also the opportunities and possibilities of related educational program in the Indian Education Sector.